Clinic and Polyclinic for Pediatric and Adolescent Medicine
PhD Student (f/m/x)
Activities and responsibilities
Project focus: Analysis of the transgenerational effect of maternal and early childhood obesity on the health of offspring.
Furthermore
- Identification of cellular as well as intercellular networks of early aging processes after perinatal stress
- Characterization of pulmonary phenotype using lung function measurements, quantitative lung morphometry and immunohistochemical and immunofluorescence-based analyses
- Flow cytometry analysis
- Independently perform physiological examinations
- Close scientific collaboration in an international team under supervision of the group leader and the PostDocs
- Analysis of collected data including storage and statistical analysis
- Writing of scientific abstracts/manuscripts and publications in peer-reviewed journals
- Participation in scientific congresses, as well as presentation of the work (poster presentations, lectures)
- Planning, management and coordination of animal experimental, cell biological as well as bioinformatic studies
Qualification profile
PhD-Requirements:
- Degree (M.Sc. or equivalent) in life sciences (e.g. medicine, biology or a comparable qualification)
- Strong interest in lung development and applied lung biology
- Excellent knowledge of English is mandatory, as the laboratory language is English
- The applicant should have an extraordinary degree of independence and initiative and be able to represent the Institute appropriately in public relations
- He/she should be a team player, creative, enthusiastic and passionate about biomedicine
- Knowledge of data storage and analysis
Expertise in the following methods:
- Knowledge of experimental models of cardiopulmonary diseases, such as animal models of as chronic hypoxia/hyperoxia and high-fat diet models
- Experience with cell biology methods
- Immunohistochemistry and immunofluorescence
- Carrying out cell culture experiments.
- Isolation and cultivation of primary cells
- Quantitative histomorphometry of the lung including organ fixation and organ harvesting
- FACS-analyses
- Experience in animal physiology and cell biology work
- Experience in animal handling and experimental design using genetic modified mice (e.g. Cre-Lox); comprehensive pathophysiological knowledge. Applicants with experience in handling laboratory animals and genetically modified mice including anesthesia and injection techniques are preferred
We offer
- A varied job in a highly interesting and challenging research topic
- A fair working environment with appreciative cooperation
- Possibility to develop side projects according to personal interests
- Internal and external training opportunities
- Flexible working time models to support family life
- Occupational health management offers